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fed wild-type mice, Nrf2 knockout mice, and Keap1 knockout mice with DDC to induce cholangitis
Nrf2 dependent proteins including HO-1 inhibits the cytokine secretion, leukocyte migration, adhesion and suppressed LPS induced production of tumor necrosis factor-a (TNF-a) and nitric oxide (NO) in murine macrophages
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The enhanced system x c activity may result from the genetic changes that occurred in CDDP-resistant cells
