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Autistic children with a co-occurring diagnosis of attention-deficit/hyperactivity disorder (ADHD, 32 ASD), anxiety disorders (1 ASD), oppositional defiant disorder (ODD, 4 ASD), dysthymia, or adjustment disorder (2 ASD) were not excluded

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These studies support the notion that early abnormalities in insulin secretion, rather than a reduction in beta cell mass, play a fundamental and primary role in early type 2 diabetes pathogenesis