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Given the wide variety of symptoms and potential long term effects of untreated B12 deficiency, its important to be aware of the signs and seek medical advice if you suspect youre affected

The amine groups of preferably lysine groups are modified with (sulfo)-SMCC rendering thiol-reactive maleimide groups on the protein

10.1016/j.cellsig.2008.06.004 [DOI] [PubMed] [Google Scholar] Keles I., Bozkurt M
