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Description
Methods Animals Animal experiments were performed with adherence to all national and local guidelines and regulations, the Guide for the Care and Use of Laboratory Animals 25 , and the ARRIVE guidelines, and with the approval of the Institutional Animal Care and Use Committee at The University of Texas Medical Branch (UTMB)
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Our data show a significant association between metformin-induced vitamin B 12 deficiency risk and a non-synonymous SNP (rs1801222) in the CBN gene, which encodes the cubilin receptor (ESM Table 6, Fig

A 2017 study used it with carboplatin followed by maintenance with Alimta alone
