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Interactions between gut microbiota and host metabolism predisposing to obesity and diabetes
Therefore, our findings suggest that pyroptosis of synovial macrophages plays a role in inducing inflammation in synovial chondrocytes and targeting synovial macrophages may be a potential therapeutic strategy for OA management
These include 2 : Secukinumab (Cosentyx) (oral), a monoclonal antibody that blocks the action of an inflammatory cytokine
