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Regarding the possible mechanisms of actions of theanine on the downregulation of the inflammatory response, the induction of NO production and GSH synthesis are likely to be critical for the prevention of hepatic diseases as well as for the improvement of immune function as shown in the study by Wang et al., 2017

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Mol Cell 40:893904 Tashkandi HM, Althagafy HS, Jaber FA, Alamri T, Al-Abbas NS, Shaer NA, Harakeh S, Hassanein EH (2023) Vinpocetine mitigates methotrexate-induced duodenal intoxication by modulating NF-B, JAK1/STAT-3, and RIPK1/RIPK3/MLKL signals