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Common Short-Term Side Effects Neuromuscular: Jaw clenching (bruxism), muscle tension, and involuntary eye movement (nystagmus) occur in most users and reflect norepinephrine-driven motor excitability

Be careful not to over-blend as it will become super foamy

Here is what to watch for: Gradual or persistent weight loss despite maintaining a reasonable appetite Chronic or recurring diarrhoea that does not fully resolve with standard treatment Reduced appetite or inconsistent interest in food Lethargy and reduced energy that does not match the dogs age or activity level A dull, dry, or poorly conditioned coat that does not reflect the diet being offered Slow recovery from illness or repeated episodes of digestive upset In more advanced cases, neurological signs such as weakness, unsteady gait, or reduced responsiveness In many long-term rescue cases, vitamin B12 deficiency has been present for months before the dog receives proper assessment

Doxorubicin activates FOXO3a to induce the expression of multidrug resistance gene ABCB1 (MDR1) in K562 leukemic cells