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The published research record is extensive for an unapproved compound hundreds of indexed animal studies, consistently favorable for treated groups across tendon, gut, and nervous-system injury models but the human evidence is thin: three small pilot studies, none controlled

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DOI: Published online: February 24, 2023 1 Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea 2 Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA Corresponding authors: Young Min Cho Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea E-mail: [email protected] Changhan Lee Leonard Davis School of Gerontology, University of Southern California, 3715 McClintock Ave, Los Angeles, CA 90089, USA E-mail: [email protected] Copyright 2023 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

Or, more likely, their effects are in general more resistant to that of heparin and less to that of warfarin, regardless of the more haemorrhage in heparin rats