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The OS data from SKB264-II-08 are still immature, but the 12-month survival rate has reached 79% (95% CI: 6787%)
Our collaborative work demonstrated that severe reactive astrocytes release excessive amounts of the inhibitory gliotransmitter GABA via bestrophin 1 (BEST1) channels, contributing to memory deficits and impairing synaptic plasticity 58,59
