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These exosomes effectively inhibit neuronal apoptosis and oxidative stress by modulating signaling pathways such as PTEN/AKT, phosphatidylinositol 3-kinase (PI3K)/AKT, and NRF2-Keap1

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24 Age-changes in GH secretory dynamics at later stages of life are clinically measurable as frank alterations of the earlier patterns that can be quantified by measurement of pulse timing and amplitude