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The published research base, predominantly preclinical with growing clinical extension, identifies several mechanisms of action

The protective effects of trehalose on cell membranes and its ability to improve the density of neutral mucins in goblet cells without adverse side effects make it a valuable component in long-term therapy for DED

Inflammation and disruption of the mucosal architecture in claudin-7 -deficient mice The claudin family members are developmentally regulated and expressed in a tissue-specific manner

This explains the gasp or choking sound followed by a deeper breath after a prolonged pause in breathing