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Mackenzie, A

PBMCs were subjected to immediate Tcell isolation as well as cell cultivation in RPMI 1640 (Invitrogen, Carlsbad, CA, USA) containing 10% heatinactivated fetal calf serum (Biochrom, Berlin, Germany), 1% HEPES (SigmaAldrich, St

Additionally, canakinumab reduces tumor cell migration to bone by blocking IL-1 from binding to its receptor, significantly decreasing the incidence and progression of breast cancer bone metastases (99)
