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Description
This methodology presents an issue with linking mechanistic actions of endocrine disrupting chemicals to the risk of disease development since endocrine dysfunction, especially within estrogenic pathways (e.g., menopausal status, menstrual cycle length, early menarche, and contraception use), are typically associated with reasons for hysterectomy (Upson and Missmer, 2020)

[DOI] [PubMed] [Google Scholar] Adams JB, Romdalvik J, Levine KE, Hu L-W

(PubMed) Ganichkin OM, Xu XM, Carlson BA, et al

Like other enzymes of the ascorbateglutathione cycle, APXs are also subjected to PTMs
