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Immunohistochemistry Immunohistochemistry for GSH was performed on formalin fixed liver specimens obtained from liver biopsies as previously described

Detailed inclusion and exclusion criteria applied for participant selection are described in the Eligibility Criteria section below

In general, NOX-family- and mitochondrial-mediated ROS generation has been considered to play a major role in the pathogenesis of oxidative-stress-related CKD complications [55]
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Both transporters have been shown to efflux folates from intestinal enterocytes and, as such, can compete with the activity of PCFT in folate uptake
