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While harnessing the immune system offers promise to clear senescent cells, the potential impact of off-target effects and unintended immune responses needs to be carefully evaluated to minimize potential harm to healthy tissues

We have good news regarding the absorption: on top of manufacturer claims, there is some data (animal study) demonstrating in can get into the skin , and it seems to be better at it than Ascorbyl Glucoside, another vitamin C derivative

STRING database (accessed on 20 September 2021).

Ca 2+ influx and cytosolic ATP depletion in erythrocytes resulted in eryptosis, with cell shrinkage and the mixing of cell membrane components [427]