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Treatment of these cultures with GH and IGF-1 lead to elevations in the level of antioxidants and reduced prooxidant levels [87]

Costedoat-Chalumeau N et al (2014) Hydroxychloroquine: a multifaceted treatment in lupus

[DOI] [PMC free article] [PubMed] [Google Scholar] [51].Boito D, Eklund A, Tisell A, et al

These findings collectively indicate that targeting HSP47either directly or via its upstream regulatory pathwaysmay effectively disrupt pathological collagen metabolism, offering novel therapeutic opportunities for IPF management
