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When two or more dimensions shift toward a pro-oxidative state, such as reduced DHODH activity due to POLQ or E2F4 inhibition, D-lactic acid accumulation triggered by CDK7-YAP-LDHD pathway disruption, or CD8 + IFN- silencing of SLC7A11, CSCs lose self-renewal capacity and become susceptible to ferroptosis

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Immunomodulatory effects of microbiota-derived metabolites at the crossroad of neurodegenerative diseases and viral infection: network-based bioinformatics insights

Vitamin C inactivates the proteasome inhibitor PS-341 in human cancer cells