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Route of Elimination In man, following a single dose of 4 mg/m2 of pentostatin infused over 5 minutes, approximately 90% of the dose was excreted in the urine as unchanged pentostatin and/or metabolites as measured by adenosine deaminase inhibitory activity

That creates a problem because it can delay detection and treatment of liver injury. Targeting Key Antioxidant In the study, which was conducted in mice, Zheng and his colleagues focused on a chemical called glutathione, which is the master antioxidant produced by the liver

As expected, the fluorescence quenching appeared to be related to the initial H 2 O 2 concentration

doi: 10.2165/00129785-200303030-00002