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Description
Furthermore, ROS-induced activation of the TGF-/Smad signaling pathway promotes tubulointerstitial fibrosis, further compromising the expression environment of OCTN2 and aggravating carnitine loss [134]

In accordance with previous work 85 , we found that gut dysbiosis correlates with fecal ImP as well as high fecal ImP/histidine ratios and anticorrelates with plasma histidine levels

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L-Carnitine transports fatty acids into mitochondria for energy production, shifting muscles to use fat instead of glycogen
