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[DOI] [PubMed] [Google Scholar] 156.Matthews R.T., Yang L., Browne S., Baik M., Beal M.F

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Rolipram, a PDE4 inhibitor, has demonstrated the ability to increase activated CREB (pCREB) levels and reduce mutant huntingtin inclusions in animal models, although it has been associated with side effects in clinical trials (Giamp et al
