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Mechanistically, heme iron activates Toll-like receptor 4 (TLR4), driving nuclear factor B (NF-B) translocation and upregulating pro-inflammatory cytokines (TNF-, IL-6)

The role of cystine-glutamate exchange in nicotine dependence in rats and humans

Drugs that affect the level of expression of hepatic enzymes, particularly those that elevate levels of glucuronosyltransferases, may increase the clearance of valproate
