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351 In the process of ferroptosis, cells are affected by oxidative stress and lipid peroxidation, resulting in the rupture of cell membranes and cell death, which is manifested mainly by the reduction in GPX4, the core enzyme of the antioxidant system (glutathione system), and the high expression of the lipid peroxidation marker 4-HNE

Godiveau M, Jahanmohan J, Abrial C, Durando X (2025) Chemotherapy-induced peripheral neuropathy in patients with breast cancer treated with taxanes (Review)

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Clinical studies performed by using nerve growth factor show that a single injection into normal individuals produces both mechanical and thermal hypersensitivity at the site of injection, which is rapid, reaching a maximum by 21 d and 3 d, respectively (39)