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Tirzepatide changes things

Recent advances in the modulation of pain by the metabotropic glutamate receptors

Interestingly, one recent study showed that small extracellular vesicles (sEVs) released from adipocytes in response to an artificial mitochondrial stress can activate a protective pathway in cardiomyocytes, exemplifying inter-organ mitohormesis in mammalian systems (Crewe et al, 2021)

Cambridge, UK: Cambridge University Press
