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Widespread rapid reductions in body size of adult salamanders in response to climate change
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Dihydrofolate reductase (DHFR) controls the regeneration of BH2 to BH4, in which NAD(P)H is the principal cofactor that supplements BH4 but not BH2

These alterations in neurotransmitter systems are further compounded by the influence of ethanol on serotonin pathways, which are critical in mood regulation
