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Accordingly, it is difficult to define strict orthologs for a given isoform among the different species and to determine what is the set of GSTU ancestors shared by angiosperms

Thus, functional characterization and analysis of regulatory aspects of gene expression of GST gene family members could help in enhancing the understanding about their role in As response and detoxification as well as evolving strategies for developing As tolerant and As-free crops through biotechnological tools in future

Mannervik B, Awasthi YC, Board PG, Hayes JD, Di Ilio C, Ketterer B, Litowsky I, Morgenstern R, Muramatsu M, Pearson WR., Picket CB, Sat K, Widersten M, Wolf C.R