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Acta Diabetologica

Most patients begin to notice symptom relief within a few days of starting the treatment, especially in cases of fatigue and mild neuropathy

[63], after 4 weeks of MNA administration (100 mg/kg), no significant differences were found between MNA-treated and untreated diabetic db/db mice with regard to the levels of fasting blood glucose and HbA1c and the body weights of the MNA-treated db/db mice did not decrease but tended to increase compared to those of the untreated db/db mice

They will examine all pregnancy complications, cases of severe illness, infant deaths and other SAEs to decide if the study should be continued, based on the predecided stopping rules