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Micronutrients should not be considered a treatment for any illness or medical condition

Aphids have developed a resistance to pyrethroids by developing resistance at the target site (knockdown resistance-kdr) (Valmorbida et al., 2022)

This is due to glutathione requiring 2 ATP for its production and, given the high abundance of glutathione (~5 mM) and rapid turnover, a material tax on the ATP pool is required to maintain glutathione antioxidant capacity

Common with retinoids (e.g., tretinoin, retinal, retinol), AHAs/BHAs (glycolic, lactic, salicylic acid), vitamin C (rarely), and exfoliating enzymes (e.g., papain)