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513 Vedolizumab, a monoclonal antibody, is used primarily for the treatment of moderate-to-severe UC by targeting 47 integrins, blocking the homing pathway of colonic lymphocytes, and reducing the inflammatory response in the intestinal tract

Stacking may flatten GH pulses and reduce natural rhythm, so this combo is generally not recommended unless cycling or alternating between them

Forman HJ, Zhang H

32: 2678-2689 [ CrossRef ] [ Google scholar ] [ PubMed ] Erdem S, Trkoglu M