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Description
Author Contributions M.K., A.D., L.P., A.S
In preclinical heart failure models, NNMT enzyme inhibition markedly reduced cardiac 1-MNA (by 77.1%), improved cardiac function, reduced left ventricular hypertrophy and fibrosis, and decreased pro-inflammatory gene expression
Nevertheless, considering all reviewed evidence together, one striking observation is the abundance of pharmacological studies observing null effects
Every cell in your body depends on mitochondria to create ATP (adenosine triphosphate), the main molecule your body uses for energy
