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Physiological Function of NNMT and the Related Metabolic Pathways NNMT is a cytosolic enzyme that catalyzes NA methylation using S-adenosyl-methionine (SAM) as a methyl donor, while producing 1-methylnicotinamide (MNA) and S-adenosyl-homocysteine (SAH)

These amino acids work together to promote the production of nitric oxide, which helps improve blood flow, delivering more oxygen and nutrients to muscles and tissues

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