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Protein misfolding and failure of clearance systems, including the autophagy-lysosome and ubiquitin-proteasome pathways, further compromise the cellular environment and lead to toxic intracellular accumulations [31, 32]

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In Vitro Display Technologies CFE has the unique benefit of enabling researchers to create a direct physical connection between a genes transcript and its protein product, generating a macromolecular complex linking genotype and phenotype

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10.1007/s12035-014-8825-3 Mol

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