glutathione conjugate of ethacrynic acid Acid: A Promising Candidate for Drug Repurposing as an Anticancer Agent Establishment of Two In Vitro
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318,319,320 Furthermore, stability can be improved without compromising drug activity by optimizing the number and modification positions of 2-F and 2-OME groups on both strands of double-stranded siRNA, leading to substantial efficacy improvements

SmythLCDRustenhovenJScotterELSchwederPFaullRLMParkTIHet al

Calder PC, Ahluwalia N, Brouns F, et al

Well, here's where things get a little hazy
