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These results suggest that excessive fat intake in ech-6 -deficient worms may be used as fuel for energy production, for instance through fatty acid -oxidation, rather than being converted into triacylglycerols for storage or into glycerophospholipids for membrane synthesis

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Summary Keywords bioavailability, ellagic acid, ellagitannins, pharmacokinetics, polyphenols, punicalagin, TMA Citation Haarhuis JE, Ahn-Jarvis J, Savva GM, Day-Walsh PE, Ferns C, Hughes S, Triller S, Al-Jaibaji O, Philo M, Acaroz E, Perez-Moral N and Kroon PA (2026) Effect of a polyphenol-rich pomegranate extract on plasma trimethylamine N-oxide levels following an oral carnitine challenge: a randomized controlled crossover trial in healthy adults