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Description
Iron regulatory proteins (IRPs), bind to iron-responsive elements (IREs) in the 5 untranslated region (UTR) of mRNAs encoding ferritin and FPN1 to inhibit their translation, while binding to IREs in the 3 UTR of TfR1 and DMT1 mRNAs to stabilize these transcripts, thereby adjusting iron storage, export, and uptake (58)
doi: 10.1016/j.bbacli.2014.09.006
In advanced-stage tumors, cancer cells frequently exhibit numerous genetic alterations and increased oxidative stress [26]
An improperly annealed quarter will have several color variations aside from the usual copper brown or black
