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Unlike some pancreatic enzymes that are activated by proteolytic cleavage (e.g., trypsinogen), pancreatic lipase is secreted in its final form

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"The majority of patients responded quickly to treatment, but two children did require ECMO therapy, and one child died as a result of a complication from ECMO with an intercranial thrombus and hemorrhage," Levin explained

Tadpoles probably remain active and grow during the winter in Louisiana but do not transform until warm weather (Dundee and Rossman, 1989)
