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Hyams Page 59 and 60: Education Council, University of Co Page 61 and 62: Hospital Medicine Robert Englander, Page 63 and 64: Ongoing research projects on an ele Page 65 and 66: Marinelli K

Interventional studies have shown that pharmacological agents targeting metabolic and hemodynamic stress, such as SGLT2 inhibitors, GLP-1 receptor agonists, and renin-angiotensin system blockers, can partially restore plasma and urinary acylcarnitine levels

it protected against CuSO4-induced reductions in seminal vesicle weight, an effect attributed to its antioxidant properties that mitigate oxidative stress and support the structural integrity of reproductive tissues 82

CAFs increase the expression of branched-chain amino acid transaminase 1 (BCAT1) under the influence of cancer cells, and the subsequent increase in the breakdown of BCAAs provides a large amount of the metabolic product branched-chain -ketoacid (BCKA) for cancer cells to maintain de novo protein synthesis and the TCA cycle [330]