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Accounting for the impact of the outlier studies, galantamine +memantine was the second-best cognitive enhancer (MD=1.87, 95% CI: 0.08 to 3.66, P-score=82%) after donepezil +memantine (MD=2.04, 95% CI: 1.03 to 3.05, P-score=92%)

In the MR-Egger regression method, weighted linear regression is performed based on the assumption that the direct effects of exposure are not influencing the associations between genetic variants and exposure (40)

An example of a condition where immunological imbalance or malfunction is thought to play a crucial role is recurrent oral ulcers (ROUs) of oral mucosa disease

J Intern Med 286(1):3240 Brydges CR et al (2021) Indoxyl sulfate, a gut microbiome-derived uremic toxin, is associated with psychic anxiety and its functional magnetic resonance imaging-based neurologic signature