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LPS is considered a psychotic agent that can activate the neuroimmune response via toll-like receptors (TLRs) present in several neuronal cell types, including microglia, endothelial cells, and astrocytes, and generate free radicals, inflammatory cytokines, and other mediators to cause inflammation and oxidative stress [6]
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Cancer Res 54 : 55315534 Karnieli E, Werner H, Rauscher II FJ, Benjamin LE, LeRoith D (1996) The IGF-I receptor gene promoter is a molecular target for the Ewing's sarcoma-Wilms' tumor 1 fusion protein
