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3) GSSG is reduced to GSH by NADPH (GR) as resumed in figure 3
Research Articles on Glutathione S Transferase Mu 1 (GSTM1)
& MacKerell, A
In addition, this deletion completely cancels the increase in ROS production caused by the gmhA deletion , while all other mutations in the genes that regulate the metabolism of cysteine and glutathione, as well as a violation of cystine transport, lead to an even greater increase in the level of ROS in cells with a gmhA deletion
