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SlizEHuilajaLPasanenALaiskTReimannEMgiRet alUniting biobank resources reveals novel genetic pathways modulating susceptibility for atopic dermatitis

The FDA this week hopefully put the final nail in this coffin with new language that should make anybody selling these products very nervous

GSH depletion causes ferroptosis in RPE cells To evaluate the mechanism of cell death in GSH-depleted cells, we treated RPE cells with various cell death pathway inhibitors including ferroptosis inhibitors ferrostatin-1 (Fer-1, 8 M), liproxstatin-1 (Lip-1, 600 nM), iron chelator deferoxamine (DFO, 80 M), pan-caspase inhibitor z-VAD-fmk (30 M) to inhibit apoptosis, autophagy inhibitor 3-methyladenine (3-MA, 10 mM), and lysosomal inhibitor bafilomycin A1 (Baf-A1, 75 nM)

Ma, Y., Guo, Z