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Gln administration significantly inhibited acute graft-versus-host disease (aGVHD)-induced inflammation and tissue damage in the spleen (43)
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Immune Enhancement: Strengthens immune defenses for greater resilience
Nfe2l2 deletion in the bone marrow-derived macrophages (BMDM) decreases the levels of GSH by downregulation of GCLM and xCT, which leads to limited the GSH availability to CTLs, thereby inhibiting antigen-induced CTLs proliferation and function [141]
