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While prompt and efficient healing of skin wounds is essential to maintaining the vital barrier function of the skin, a pathological wound healing response can result in abnormal extracellular matrix (ECM) deposition and diminished degradation, ultimately leading to scarring and fibrosis (Figure 2)

In the process of developing new drugs, pre-formulation studies are crucial because they give formulation development a solid scientific foundation

It increases the expression of AAK-1 through the persulfidation of cysteine residues in ETS domain-containing protein Elk-4 (ELK4), thereby inhibiting CD8 + T cell migration and immunity (157)

doi: 10.1212/01.WNL.0000152046.11390.45 6