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Some researchers compensate by adding an extra 0.1-0.2mL of bacteriostatic water during reconstitution, accepting a slightly lower concentration in exchange for more usable doses

So while the doseresponse supports the CagriSema hypothesis, it also predicts that even a very high-efficacy weight-loss agent would need a dedicated, adequately long liver trial to demonstrate a fibrosis benefit
A 3 mL syringe has a different scale than a U-100 insulin syringe

Clin Pharmacol Ther 83 , 160166, (2008)