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PMID: 148 SpeckmannBGruneT

Moreover, the metabolism of -KG also circumvents the requirement for glutamine deamination, a process that may result in neurotoxic ammonium accumulation in ATM-deficient cells

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The anti-inflammatory effect of choline was confirmed ex vivo, where endotoxin-activated human whole blood and macrophages exposed to supraphysiological choline concentrations (between 150 mM) exhibited reduced TNF- production (250)
