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The adipose tissue acts as a regulator of fatty acid release and storage and alternates between lipolysis and lipogenesis
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Since these studies suggested that SLC7A11 inactivation-induced apoptosis is likely driven by GSH depletion and ROS induction, it remains to be established how GSH depletion resulting from SLC7A11 inactivation can induce different modes of cell death (ferroptosis vs apoptosis) under different conditions or contexts
