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3) through modification of viral replication machinery and, in some cases, host proteins by nitration, S-nitrosylation, and oxidation [119]

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Patient adherence has been negatively impacted by a combination of factors including myths and misconceptions about corticosteroid medications (as discussed in a 5 minute video by the American Academy of Allergy Asthma & Immunology), and fear of adverse effects that are most commonly observed in severe asthmatics taking high doses, but which can also impact some patients taking lower doses as well (Heffler et al, 2018)