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2.1.3.3 Other biological molecules and structures linked to the neurovascular theory of migraine 2.1.3.3.1 Pituitary adenylate cyclase-activating peptide (PACAP) Pituitary adenylate cyclase-activating peptide (PACAP) is another molecule that is suspected to play a role in migraine

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Although this might be seen as a positive for increasing cysteine and glutathione, in fact it is thought that the excess of cystathionine is overall negative and could flood and impair the other pathways below, or specifically increase ammonia