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Description
The suppression of autophagy, either through genetic approaches (e.g., knockout of autophagy-related genes like ATG5 ) or pharmacological inhibitors (e.g., chloroquine [CQ] or hydroxychloroquine [HCQ]), has been demonstrated to reduce tumor growth and to increase sensitivity to chemotherapy [112,113,114]

The audience or readers interested in this work may be a population, scientific or not, interested in natural products such as Punica granatum (pomegranate) as alternative treatment for psychiatric disorders and cases of anxiety and depression, which are more commonly found in general consumption in populations with chronic pain compared to the other two psychiatric disorders

During ICD, DAMPs and pathogen-associated molecular patterns bind to pattern recognition receptors, generating anti-tumor immune responses

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