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The pooled results, however, of two trials suggested that treatment with recombinant human IGF-1 might be beneficial, but in one study no benefit in survival was found 19

doi: 10.1097/CM9.0000000000001474 2 Sarmento-RibeiroABScorilasAGoncalvesACEfferthTTrougakosIP

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[2] [12] Deficiency is especially harmful in pregnancy, childhood, and older adults
