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Antiglycating [edit] Carnosine acts as an antiglycating agent, reducing the rate of formation of advanced glycation end-products (substances that can be a factor in the development or worsening of many degenerative diseases, such as diabetes, atherosclerosis, chronic kidney failure, and Alzheimer's disease [14] ), and ultimately reducing development of atherosclerotic plaque build-up

OCT2: organic cation transporter 2 Activation of NF-B signaling by TMAO and its contribution to atherosclerosis, thrombosis, and inflammation-related diseases

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Citrulline : A 2011 study found citrulline to improve ED symptoms, although citrulline was less effective than PDE5 inhibitors